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$40.15
−0.67%Market closedDelayed 15 minutes · Source: ViewTrade · 5 Nov 2026, 06:25 IST · A quote does not mean the product is available to trade on your account.
In brief
Questions investors ask
Quotes run fifteen minutes behind.
Closed at $40.15 on 4 Nov 2026: 53.7% below the 52-week high of $86.74 (8 Jul 2026) and 2.1% above the low of $39.33 (4 Nov 2026).
Daily price bars, split-adjusted · as of 4 Nov 2026
1 month: −8.8% (SPY −1.6%, XLV +13.5%). 3 months: −25.9% (SPY −0.4%, XLV +15.5%). 1 year: −44.9% (SPY +13.6%, XLV +30.7%). Price change to the 4 Nov 2026 close; dividends excluded.
Daily closes, split-adjusted: IONS, SPY and XLV · as of 4 Nov 2026
20.7M shares were sold short at the 15 Oct 2026 settlement, 12.4% of the 166.2M shares outstanding; covering them would take 7.7 days of average volume. Short interest is reported twice a month, on a lag.
Exchange short-interest filing · as of 15 Oct 2026
The 4 Nov 2026 close of $40.15 was 15.9% below its 50-day average ($47.75) and 39.4% below its 200-day average ($66.24). It has closed below the 200-day for 84 sessions, since 9 Jul 2026. The 50-day average crossed below the 200-day on 17 Jun 2026, 97 sessions ago.
Daily closes, split-adjusted; 50- and 200-session simple averages · as of 4 Nov 2026
Price return, split-adjusted
At the 4 Nov 2026 close
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).
July 9, 2026
−23.90%September 2, 2025
+34.84%May 9, 2022
−12.64%